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Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer
Dipeptidyl peptidases 8 and 9 are intracellular N-terminal dipeptidyl peptidases (preferentially postproline) associated with pathophysiological roles in immune response and cancer biology. While the DPP family member DPP4 is extensively characterized in molecular terms as a validated therapeutic ta...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816189/ https://ncbi.nlm.nih.gov/pubmed/29382749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717565115 |
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