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Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria

The emergence and ongoing spread of multidrug-resistant bacteria puts humans and other species at risk for potentially lethal infections. Thus, novel antibiotics or alternative approaches are needed to target drug-resistant bacteria, and metabolic modulation has been documented to improve antibiotic...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Su, Yu-bin, Peng, Bo, Li, Hui, Cheng, Zhi-xue, Zhang, Tian-tuo, Zhu, Jia-xin, Li, Dan, Li, Min-yi, Ye, Jin-zhou, Du, Chao-chao, Zhang, Song, Zhao, Xian-liang, Yang, Man-jun, Peng, Xuan-xian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816162/
https://ncbi.nlm.nih.gov/pubmed/29382755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714645115
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