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High-dose amikacin for achieving serum target levels in critically ill elderly patients

INTRODUCTION: To achieve target concentrations, the application of higher-than-standard doses of amikacin is proposed for the treatment of sepsis due to an increase in volume of distribution and clearance, but little data are available on aminoglycoside administration in critically ill elderly patie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Drug Resist
Hauptverfasser: Sadeghi, Kourosh, Hamishehkar, Hadi, Najmeddin, Farhad, Ahmadi, Arezoo, Hazrati, Ebrahim, Honarmand, Hooshyar, Mojtahedzadeh, Mojtaba
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815475/
https://ncbi.nlm.nih.gov/pubmed/29483780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S150839
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