BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells

The embryonic formation of midbrain dopaminergic (mDA) neurons in vivo provides critical guidelines for the in vitro differentiation of mDA neurons from stem cells, which are currently being developed for Parkinson's disease cell replacement therapy. Bone morphogenetic protein (BMP)/SMAD inhibi...

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Pubblicato in:J Neurosci
Autori principali: Jovanovic, Vukasin M., Salti, Ahmad, Tilleman, Hadas, Zega, Ksenija, Jukic, Marin M., Zou, Hongyan, Friedel, Roland H., Prakash, Nilima, Blaess, Sandra, Edenhofer, Frank, Brodski, Claude
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815451/
https://ncbi.nlm.nih.gov/pubmed/29321139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1540-17.2018
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