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Dynamic m(6)A modification regulates local translation of mRNA in axons

N (6)-methyladenosine (m(6)A) is a reversible modification in mRNA and has been shown to regulate processing, translation and decay of mRNA. However, the roles of m(6)A modification in neuronal development are still not known. Here, we found that the m(6)A eraser FTO is enriched in axons and can be...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yu, Jun, Chen, Mengxian, Huang, Haijiao, Zhu, Junda, Song, Huixue, Zhu, Jian, Park, Jaewon, Ji, Sheng-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815124/
https://ncbi.nlm.nih.gov/pubmed/29186567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1182
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