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Dynamic m(6)A modification regulates local translation of mRNA in axons

N (6)-methyladenosine (m(6)A) is a reversible modification in mRNA and has been shown to regulate processing, translation and decay of mRNA. However, the roles of m(6)A modification in neuronal development are still not known. Here, we found that the m(6)A eraser FTO is enriched in axons and can be...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Yu, Jun, Chen, Mengxian, Huang, Haijiao, Zhu, Junda, Song, Huixue, Zhu, Jian, Park, Jaewon, Ji, Sheng-Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815124/
https://ncbi.nlm.nih.gov/pubmed/29186567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1182
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