A peculiar IclR family transcription factor regulates para-hydroxybenzoate catabolism in Streptomyces coelicolor

In Streptomyces coelicolor, we identified a para-hydroxybenzoate (PHB) hydroxylase, encoded by gene pobA (SCO3084), which is responsible for conversion of PHB into PCA (protocatechuic acid), a substrate of the β-ketoadipate pathway which yields intermediates of the Krebs cycle. We also found that th...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Zhang, Rui, Lord, Dana M, Bajaj, Rakhi, Peti, Wolfgang, Page, Rebecca, Sello, Jason K
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814911/
https://ncbi.nlm.nih.gov/pubmed/29240934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1234
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