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Diverged Plant Terpene Synthases Reroute the Carbocation Cyclization Path towards the Formation of Unprecedented 6/11/5 and 6/6/7/5 Sesterterpene Scaffolds

Sesterterpenoids are a relatively rare class of plant terpenes. Sesterterpene synthase (STS)‐mediated cyclization of the linear C(25) isoprenoid precursor geranylfarnesyl diphosphate (GFPP) defines sesterterpene scaffolds. So far only a very limited number of STSs have been characterized. The discov...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Huang, Ancheng C., Hong, Young J., Bond, Andrew D., Tantillo, Dean J., Osbourn, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814883/
https://ncbi.nlm.nih.gov/pubmed/29194888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201711444
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