Oleate activates SREBP-1 signaling activity in SCD1-deficient hepatocytes

Stearoyl-CoA desaturase-1 (SCD1) is a key player in lipid metabolism. SCD1 catalyzes the synthesis of monounsaturated fatty acids (MUFA). MUFA are then incorporated into triacylglycerols and phospholipids. Previous studies have shown that Scd1 deficiency in mice induces metabolic changes in the live...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Lounis, Mohamed A., Bergeron, Karl-F., Burhans, Maggie S., Ntambi, James M., Mounier, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814596/
https://ncbi.nlm.nih.gov/pubmed/28851735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00151.2017
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