Enhanced release of acid sphingomyelinase-enriched exosomes generates a lipidomics signature in CSF of Multiple Sclerosis patients

Multiple Sclerosis (MuS) is a complex multifactorial neuropathology, resulting in heterogeneous clinical presentation. A very active MuS research field concerns the discovery of biomarkers helpful to make an early and definite diagnosis. The sphingomyelin pathway has emerged as a molecular mechanism...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pieragostino, Damiana, Cicalini, Ilaria, Lanuti, Paola, Ercolino, Eva, di Ioia, Maria, Zucchelli, Mirco, Zappacosta, Romina, Miscia, Sebastiano, Marchisio, Marco, Sacchetta, Paolo, Onofrj, Marco, Del Boccio, Piero
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814401/
https://ncbi.nlm.nih.gov/pubmed/29449691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21497-5
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