Microsatellite instability is a biomarker for immune checkpoint inhibitors in endometrial cancer

In recent years, it has become evident that tumor cells have immune escape mechanisms, and immune checkpoint inhibitor therapy (anti-PD-1/PD-L1 antibody) has shown benefit in various cancers. In endometrial tumors with microsatellite-instability (MSI), somatic mutations have the potential to encode...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yamashita, Hitomi, Nakayama, Kentaro, Ishikawa, Masako, Nakamura, Kohei, Ishibashi, Tomoka, Sanuki, Kaori, Ono, Ruriko, Sasamori, Hiroki, Minamoto, Toshiko, Iida, Kouji, Sultana, Razia, Ishikawa, Noriyoshi, Kyo, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814165/
https://ncbi.nlm.nih.gov/pubmed/29464025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23790
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