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Autocatalytic microtubule nucleation determines the size and mass of Xenopus laevis egg extract spindles

Regulation of size and growth is a fundamental problem in biology. A prominent example is the formation of the mitotic spindle, where protein concentration gradients around chromosomes are thought to regulate spindle growth by controlling microtubule nucleation. Previous evidence suggests that micro...

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Publicat a:eLife
Autors principals: Decker, Franziska, Oriola, David, Dalton, Benjamin, Brugués, Jan
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814149/
https://ncbi.nlm.nih.gov/pubmed/29323637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31149
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