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Selective targeting of tumor associated macrophages in different tumor models

Tumor progression largely depends on the presence of alternatively polarized (M2) tumor-associated macrophages (TAMs), whereas the classical M1-polarized macrophages can promote anti-tumorigenic immune responses. Thus, selective inhibition of M2-TAMs is a desirable anti-cancer approach in highly res...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kakoschky, Bianca, Pleli, Thomas, Schmithals, Christian, Zeuzem, Stefan, Brüne, Bernhard, Vogl, Thomas J., Korf, Horst-Werner, Weigert, Andreas, Piiper, Albrecht
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814016/
https://ncbi.nlm.nih.gov/pubmed/29447241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193015
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