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Using DR52c/Ni(2+) mimotope tetramers to detect Ni(2+) reactive CD4(+) T cells in patients with joint replacement failure

T cell mediated hypersensitivity to nickel (Ni(2+)) is one of the most common causes of allergic contact dermatitis. Ni(2+) sensitization may also contribute to the failure of Ni(2+) containing joint implants, and revision to non-Ni(2+) containing hardware can be costly and debilitating. Previously,...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Zhang, Yan, Wang, Yang, Anderson, Kirsten, Novikov, Andrey, Liu, Zikou, Pacheco, Karin, Dai, Shaodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813678/
https://ncbi.nlm.nih.gov/pubmed/28554661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.05.020
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