ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity

Atypical chemokine receptors (ACKRs) are regulators of leukocyte traffic, inflammation, and immunity. ACKR2 is a scavenger for most inflammatory CC chemokines and is a negative regulator of inflammation. Here we report that ACKR2 is expressed in hematopoietic precursors and downregulated during myel...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Massara, Matteo, Bonavita, Ornella, Savino, Benedetta, Caronni, Nicoletta, Mollica Poeta, Valeria, Sironi, Marina, Setten, Elisa, Recordati, Camilla, Crisafulli, Laura, Ficara, Francesca, Mantovani, Alberto, Locati, Massimo, Bonecchi, Raffaella
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813042/
https://ncbi.nlm.nih.gov/pubmed/29445158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03080-8
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