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Attenuation of genome-wide 5-methylcytosine level is an epigenetic feature of cutaneous malignant melanomas
Epigenetic modification of DNA, namely covalent changes of cytosine residues, plays a key role in the maintenance of inactive chromatin regions, both in health and in disease. In the vast majority of malignant melanomas, the most notable known epigenetic abnormality is the attenuation of 5-hydroxyme...
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| 出版年: | Melanoma Res |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812886/ https://ncbi.nlm.nih.gov/pubmed/27997431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000315 |
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