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Attenuation of genome-wide 5-methylcytosine level is an epigenetic feature of cutaneous malignant melanomas
Epigenetic modification of DNA, namely covalent changes of cytosine residues, plays a key role in the maintenance of inactive chromatin regions, both in health and in disease. In the vast majority of malignant melanomas, the most notable known epigenetic abnormality is the attenuation of 5-hydroxyme...
Guardado en:
| Publicado en: | Melanoma Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812886/ https://ncbi.nlm.nih.gov/pubmed/27997431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000315 |
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