Neuronal exosomes reveal Alzheimer’s disease biomarkers in Down syndrome

INTRODUCTION: Individuals with Down syndrome (DS) exhibit Alzheimer’s disease (AD) neuropathology and dementia early in life. Blood biomarkers of AD neuropathology would be valuable, as non-AD intellectual disabilities of DS and AD dementia overlap clinically. We hypothesized that elevations of amyl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Alzheimers Dement
Main Authors: Hamlett, Eric D., Goetzl, Edward J., Ledreux, Aurélie, Vasilevko, Vitaly, Boger, Heather A., LaRosa, Angela, Clark, David, Carroll, Steven L., Iragui, Maria Carmona, Fortea, Juan, Mufson, Elliott J., Sabbagh, Marwan, Mohammed, Abdul H., Hartley, Dean, Doran, Eric, Lott, Ira T., Granholm, Ann-Charlotte
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812672/
https://ncbi.nlm.nih.gov/pubmed/27755974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.08.012
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