‘Future-proofing’ blood processing for measurement of circulating microRNAs in samples from biobanks and prospective clinical trials

BACKGROUND: Quantifying circulating nucleic-acids is an important new approach to cancer diagnosis/monitoring. METHODS: We compared the suitability of serum versus plasma for measuring microRNAs using RT-qPCR and assessed how pre-analytical variables that can affect circulating-tumor-DNA (ctDNA) qua...

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Détails bibliographiques
Publié dans:Cancer Epidemiol Biomarkers Prev
Auteurs principaux: Murray, Matthew J., Watson, Hannah L., Ward, Dawn, Bailey, Shivani, Ferraresso, Marta, Nicholson, James C., Gnanapragasam, Vincent J., Thomas, Benjamin, Scarpini, Cinzia G., Coleman, Nicholas
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812437/
https://ncbi.nlm.nih.gov/pubmed/29254935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-17-0657
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