Haploidentical HSCT for hemoglobinopathies: improved outcomes with TCRαβ(+)/CD19(+)-depleted grafts

We examined outcomes of haploidentical hematopoietic cell transplantation (haplo-HCT) using T-cell receptor αβ(+) (TCRαβ(+))/CD19(+)-depleted grafts (TCR group, 14 patients) in children with hemoglobinopathies. Patients received a preparative regimen consisting of busulfan, thiotepa, cyclophosphamid...

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Vydáno v:Blood Adv
Hlavní autoři: Gaziev, Javid, Isgrò, Antonella, Sodani, Pietro, Paciaroni, Katia, De Angelis, Gioia, Marziali, Marco, Ribersani, Michela, Alfieri, Cecilia, Lanti, Alessandro, Galluccio, Tiziana, Adorno, Gaspare, Andreani, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812329/
https://ncbi.nlm.nih.gov/pubmed/29431621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012005
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