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1α,25-dihydroxyvitamin D(3) mitigates cancer cell mediated mitochondrial dysfunction in human skeletal muscle cells

Cancer cachexia is associated with muscle weakness and atrophy. We investigated whether 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)), which has previously been shown to increase skeletal myoblast oxygen consumption rate, could reverse the deleterious effects of tumor cell conditioned medium on myo...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Ryan, Zachary C., Craig, Theodore A., Wang, Xuewei, Delmotte, Philippe, Salisbury, Jeffrey L., Lanza, Ian R., Sieck, Gary C., Kumar, Rajiv
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812288/
https://ncbi.nlm.nih.gov/pubmed/29366785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.01.092
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