CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes

CD5 is constitutively expressed on T cells and a subset of mature normal and leukemic B cells in patients with chronic lymphocytic leukemia (CLL). Important functional properties are associated with CD5 expression in B cells, including signal transducer and activator of transcription 3 activation, I...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Garaud, Soizic, Taher, Taher E, Debant, Marjolaine, Burgos, Miguel, Melayah, Sarra, Berthou, Christian, Parikh, Kaushal, Pers, Jacques-Olivier, Luque-Paz, Damien, Chiocchia, Gilles, Peppelenbosch, Maikel, Isenberg, David A, Youinou, Pierre, Mignen, Olivier, Renaudineau, Yves, Mageed, Rizgar A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811677/
https://ncbi.nlm.nih.gov/pubmed/27499044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.42
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