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The Histone Demethylase JMJD2A Modulates the Induction of Hypertrophy Markers in iPSC-Derived Cardiomyocytes

The development of cardiovascular pathologies is partly attributed to epigenetic causes, including histone methylation, which appears to be an important marker in hearts that develop cardiac hypertrophy. Previous studies showed that the histone demethylase JMJD2A can regulate the hypertrophic proces...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Rosales, Wendy, Lizcano, Fernando
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811633/
https://ncbi.nlm.nih.gov/pubmed/29479368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00014
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