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A chemoenzymatic process for amide bond formation by an adenylating enzyme-mediated mechanism

Amide bond formation serves as a fundamental reaction in chemistry, and is practically useful for the synthesis of peptides, food additives, and polymers. However, current methods for amide bond formation essentially generate wastes and suffer from poor atom economy under harsh conditions. To solve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hara, Ryotaro, Hirai, Kengo, Suzuki, Shin, Kino, Kuniki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811625/
https://ncbi.nlm.nih.gov/pubmed/29440726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21408-8
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