Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated, and cultured on a porous membrane within a mi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kasendra, Magdalena, Tovaglieri, Alessio, Sontheimer-Phelps, Alexandra, Jalili-Firoozinezhad, Sasan, Bein, Amir, Chalkiadaki, Angeliki, Scholl, William, Zhang, Cheng, Rickner, Hannah, Richmond, Camilla A., Li, Hu, Breault, David T., Ingber, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811607/
https://ncbi.nlm.nih.gov/pubmed/29440725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21201-7
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