The Fate of a Hapten - From the Skin to Modification of Macrophage Migration Inhibitory Factor (MIF) in Lymph Nodes

Skin (contact) allergy, the most prevalent form of immunotoxicity in humans, is caused by low molecular weight chemicals (haptens) that penetrate stratum corneum and modify endogenous proteins. The fate of haptens after cutaneous absorption, especially what protein(s) they react with, is largely unk...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Karlsson, Isabella, Samuelsson, Kristin, Simonsson, Carl, Stenfeldt, Anna-Lena, Nilsson, Ulrika, Ilag, Leopold L., Jonsson, Charlotte, Karlberg, Ann-Therese
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811565/
https://ncbi.nlm.nih.gov/pubmed/29440696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21327-8
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