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Rpb9-deficient cells are defective in DNA damage response and require histone H3 acetylation for survival

Rpb9 is a non-essential subunit of RNA polymerase II that is involved in DNA transcription and repair. In budding yeast, deletion of RPB9 causes several phenotypes such as slow growth and temperature sensitivity. We found that simultaneous mutation of multiple N-terminal lysines within histone H3 wa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Sein, Henel, Reinmets, Kristina, Peil, Kadri, Kristjuhan, Kersti, Värv, Signe, Kristjuhan, Arnold
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811553/
https://ncbi.nlm.nih.gov/pubmed/29440683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21110-9
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