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Rpb9-deficient cells are defective in DNA damage response and require histone H3 acetylation for survival
Rpb9 is a non-essential subunit of RNA polymerase II that is involved in DNA transcription and repair. In budding yeast, deletion of RPB9 causes several phenotypes such as slow growth and temperature sensitivity. We found that simultaneous mutation of multiple N-terminal lysines within histone H3 wa...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811553/ https://ncbi.nlm.nih.gov/pubmed/29440683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21110-9 |
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