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Mammalian Cells Undergo Endoreduplication in Response to Lactic Acidosis

Polyploidization, a common event during the evolution of different tumours, has been proposed to confer selective advantages to tumour cells by increasing the occurrence of mutations promoting cancer progression and by conferring chemotherapy resistance. While conditions leading to polyploidy in can...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tan, Zhihao, Chu, De Zhi Valerie, Chan, Yong Jie Andrew, Lu, Yi Ena, Rancati, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811548/
https://ncbi.nlm.nih.gov/pubmed/29440645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20186-7
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