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Mutations in the Drosophila homolog of human PLA2G6 give rise to age-dependent loss of psychomotor activity and neurodegeneration

Infantile neuroaxonal dystrophy (INAD) is a fatal neurodegenerative disorder that typically begins within the first few years of life and leads to progressive impairment of movement and cognition. Several years ago, it was shown that >80% of patients with INAD have mutations in the phospholipase...

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Publicat a:Sci Rep
Autors principals: Iliadi, Konstantin G., Gluscencova, Oxana B., Iliadi, Natalia, Boulianne, Gabrielle L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811537/
https://ncbi.nlm.nih.gov/pubmed/29440694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21343-8
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