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Panton–Valentine Leukocidin Colocalizes with Retinal Ganglion and Amacrine Cells and Activates Glial Reactions and Microglial Apoptosis

Experimental models have established Panton–Valentine leukocidin (PVL) as a potential critical virulence factor during Staphylococcus aureus endophthalmitis. In the present study, we aimed to identify retinal cell targets for PVL and to analyze early retinal changes during infection. After the intra...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, XuanLi, Heitz, Pauline, Roux, Michel, Keller, Daniel, Bourcier, Tristan, Sauer, Arnaud, Prévost, Gilles, Gaucher, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811455/
https://ncbi.nlm.nih.gov/pubmed/29440661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20590-z
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