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Disruption of Thyroid Hormone Sulfotransferase Activity by Brominated Flame Retardant Chemicals in the Human Choriocarcinoma Placenta Cell Line, BeWo

Brominated flame retardants (BFRs) have been shown to disrupt thyroid hormone (TH) homeostasis through multiple mechanisms, including inhibition of enzymes that regulate intracellular levels of THs, such as sulfotransferases (SULTs). The placenta plays a critical role in helping to maintain TH level...

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Detalhes bibliográficos
Publicado no:Chemosphere
Main Authors: Leonetti, Christopher P., Butt, Craig M., Stapleton, Heather M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811394/
https://ncbi.nlm.nih.gov/pubmed/29331935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemosphere.2017.12.172
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