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Using imputed genotype data in the joint score tests for genetic association and gene-environment interactions in case-control studies
Genome-wide association studies (GWAS) are now routinely imputed for untyped SNPs based on various powerful statistical algorithms for imputation trained on reference datasets. The use of predicted allele counts for imputed SNPs as the dosage variable is known to produce valid score test for genetic...
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| Publicado no: | Genet Epidemiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811375/ https://ncbi.nlm.nih.gov/pubmed/29178451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22093 |
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