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Intramolecular ring-opening from a CO(2)-derived nucleophile as the origin of selectivity for 5-substituted oxazolidinone from the (salen)Cr-catalyzed [aziridine + CO(2)] coupling

The (salen)Cr-catalyzed [aziridine + CO(2)] coupling to form oxazolidinone was found to exhibit excellent selectivity for the 5-substituted oxazolidinone product in the absence of any cocatalyst. Quantum mechanical calculations suggest that the preferential opening of the substituted C–N bond of the...

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Опубликовано в: :Chem Sci
Главные авторы: Adhikari, Debashis, Miller, Aaron W., Baik, Mu-Hyun, Nguyen, SonBinh T.
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811137/
https://ncbi.nlm.nih.gov/pubmed/29560215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02785j
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