Neutralizing antibodies against adeno-associated viruses in Sjögren’s patients: implications for gene therapy

One potential setback to the use of gene therapy for the treatment of Sjögren’s syndrome is the presence of neutralizing antibodies (nAb) against adeno-associated virus (AAV) serotypes. In order to evaluate the efficacy of this treatment option, nAb titers were measured in both healthy individuals a...

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Vydáno v:Gene Ther
Hlavní autoři: Corden, A, Handelman, B, Yin, H, Cotrim, A, Alevizos, I, Chiorini, JA
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810933/
https://ncbi.nlm.nih.gov/pubmed/28150697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2017.1
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