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One (sub-)acinus for all: Fate of inhaled aerosols in heterogeneous pulmonary acinar structures

Computational Fluid Dynamics (CFD) have offered an attractive gateway to investigate in silico respiratory flows and aerosol transport in the depths of the lungs. Yet, not only do existing models lack sufficient anatomical realism in capturing the heterogeneity and morphometry of the acinar environm...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Sci
Main Authors: Hofemeier, Philipp, Koshiyama, Kenishiro, Wada, Shigeo, Sznitman, Josué
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810902/
https://ncbi.nlm.nih.gov/pubmed/28954217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2017.09.033
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