Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma

Glioblastoma (GBM) is the most common primary brain cancer in adults and is notoriously difficult to treat because of its diffuse nature. We performed single-cell RNA sequencing (RNA-seq) on 3,589 cells in a cohort of four patients. We obtained cells from the tumor core as well as surrounding periph...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Darmanis, Spyros, Sloan, Steven A., Croote, Derek, Mignardi, Marco, Chernikova, Sophia, Samghababi, Peyman, Zhang, Ye, Neff, Norma, Kowarsky, Mark, Caneda, Christine, Li, Gordon, Chang, Steven D., Connolly, Ian David, Li, Yingmei, Barres, Ben A., Gephart, Melanie Hayden, Quake, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810554/
https://ncbi.nlm.nih.gov/pubmed/29091775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.030
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