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Selecting cases and controls for DNA sequencing studies using family histories of disease

Recent improvements in sequencing technology have enabled the investigation of so-called missing heritability, and a large number of affected subjects have been sequenced in order to detect significant associations between human diseases and rare variants. However, the cost of genome sequencing is s...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Kim, Wonji, Qiao, Dandi, Cho, Michael H., Kwak, Soo Heon, Park, Kyong Soo, Silverman, Edwin K., Sham, Pak, Won, Sungho
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810411/
https://ncbi.nlm.nih.gov/pubmed/28222494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7248
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