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Surprising outcomes in cannabinoid CB1/CB2 receptor double knockout mice in two models of ischemia

AIMS: We tested the hypothesis that CB1/CB2 receptor double knockout would produce significant increases in infarct size and volume and significant worsening in clinical score, using two mouse models, one of permanent ischemia and one of ischemia/reperfusion. MAIN METHODS: Focal cerebral infarcts we...

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Bibliografiske detaljer
Udgivet i:Life Sci
Main Authors: Ward, Sara Jane, Castelli, Francesca, Reichenbach, Zachary W., Tuma, Ronald F.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810406/
https://ncbi.nlm.nih.gov/pubmed/29288767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2017.12.030
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