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Increased expression of sterol regulatory element binding protein-2 alleviates autophagic dysfunction in NAFLD

Sterol regulatory element binding protein-2 (SREBP-2) is an important transcription factor in lipid homeostasis. A previous study showed that SREBP-2 also activated autophagic genes during cell-sterol depletion. Alterations in autophagy are reported to be involved in the pathogenesis of nonalcoholic...

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Vydáno v:Int J Mol Med
Hlavní autoři: Cheng, Chunwei, Deng, Xiaoling, Xu, Keshu
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810215/
https://ncbi.nlm.nih.gov/pubmed/29336468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3389
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