Monitoring of argatroban and lepirudin anticoagulation in critically ill patients by conventional laboratory parameters and rotational thromboelastometry – a prospectively controlled randomized double-blind clinical trial

BACKGROUND: Argatroban or lepirudin anticoagulation therapy in patients with heparin induced thrombocytopenia (HIT) or HIT suspect is typically monitored using the activated partial thromboplastin time (aPTT). Although aPTT correlates well with plasma levels of argatroban and lepirudin in healthy vo...

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Detalhes bibliográficos
Publicado no:BMC Anesthesiol
Main Authors: Beiderlinden, Martin, Werner, Patrick, Bahlmann, Astrid, Kemper, Johann, Brezina, Tobias, Schäfer, Maximilian, Görlinger, Klaus, Seidel, Holger, Kienbaum, Peter, Treschan, Tanja A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810183/
https://ncbi.nlm.nih.gov/pubmed/29426286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-018-0475-y
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