Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea

BACKGROUND: Recently, increased tumor incidence and cancer-related mortality have been reported among patients with obstructive sleep apnea (OSA). Intermittent hypoxia (IH), the hallmark feature of OSA, contributes to the metastasis of tumors. However, the molecular mechanisms by which tumor metasta...

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Vydáno v:Respir Res
Hlavní autoři: Li, Lian, Ren, Fangyuan, Qi, Chao, Xu, Leiqian, Fang, Yinshan, Liang, Maoli, Feng, Jing, Chen, Baoyuan, Ning, Wen, Cao, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809953/
https://ncbi.nlm.nih.gov/pubmed/29433520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0727-x
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