Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea

BACKGROUND: Recently, increased tumor incidence and cancer-related mortality have been reported among patients with obstructive sleep apnea (OSA). Intermittent hypoxia (IH), the hallmark feature of OSA, contributes to the metastasis of tumors. However, the molecular mechanisms by which tumor metasta...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Li, Lian, Ren, Fangyuan, Qi, Chao, Xu, Leiqian, Fang, Yinshan, Liang, Maoli, Feng, Jing, Chen, Baoyuan, Ning, Wen, Cao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809953/
https://ncbi.nlm.nih.gov/pubmed/29433520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0727-x
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