Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer

BACKGROUND: Patient-derived xenograft (PDX) models with definite molecular signature are attractive preclinical models for development of novel targeted drugs. Here, we profiled and explored potential therapeutic targets based on characterized PDX models for advanced gastric cancer (AGC). METHODS: T...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Chen, Zuhua, Huang, Wenwen, Tian, Tiantian, Zang, Wanchun, Wang, Jingyuan, Liu, Zhentao, Li, Zhongwu, Lai, Yumei, Jiang, Zhi, Gao, Jing, Shen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809945/
https://ncbi.nlm.nih.gov/pubmed/29433585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0563-y
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