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Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening

Organophosphate-based compounds (OPs) represent a significant threat to warfighters (nerve agents) and civilian populations (pesticides). There is a pressing need to develop in vitro brain models that correlate to the in vivo brain to rapidly study OPs for neurotoxicity. Here we report on a microflu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Koo, Youngmi, Hawkins, Brian T., Yun, Yeoheung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809488/
https://ncbi.nlm.nih.gov/pubmed/29434277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20876-2
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