Nemopilema nomurai jellyfish venom exerts an anti-metastatic effect by inhibiting Smad- and NF-κB-mediated epithelial–mesenchymal transition in HepG2 cells

Epithelial–mesenchymal transition (EMT) is a key initial step in metastasis for malignant cancer cells to obtain invasive and motile properties. Inhibiting EMT has become a new strategy for cancer therapy. In our previous in vivo study, Nemopilema nomurai jellyfish venom (NnV) -treated HepG2 xenogra...

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Udgivet i:Sci Rep
Main Authors: Lee, Hyunkyoung, Pyo, Min Jung, Bae, Seong Kyeong, Heo, Yunwi, Choudhary, Indu, Hwang, Duhyeon, Yang, Hyeryeon, Kim, Je-hein, Chae, Jinho, Han, Chang Hoon, Kang, Changkeun, Yum, Seungshic, Kim, Euikyung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809415/
https://ncbi.nlm.nih.gov/pubmed/29434219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20724-3
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