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Characterization of Retinal Ganglion Cell and Optic Nerve Phenotypes Caused by Sustained Intracranial Pressure Elevation in Mice

Elevated intracranial pressure (ICP) can result in multiple neurologic sequelae including vision loss. Inducible models of ICP elevation are lacking in model organisms, which limits our understanding of the mechanism by which increased ICP impacts the visual system. We adapted a mouse model for the...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Shen, Guofu, Link, Schuyler, Kumar, Sandeep, Nusbaum, Derek M., Tse, Dennis Y., Fu, Yingbin, Wu, Samuel M., Frankfort, Benjamin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809383/
https://ncbi.nlm.nih.gov/pubmed/29434244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21254-8
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