Inhibition of Mammalian Target of Rapamycin Signaling with Rapamycin Prevents Trauma-Induced Heterotopic Ossification

A pressing clinical need exists for 63% to 65% of combat-wounded service members and 11% to 20% of civilians who develop heterotopic ossification (HO) after blast-related extremity injury and traumatic injuries, respectively. The mammalian target of rapamycin pathway is a central cellular sensor of...

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Publicat a:Am J Pathol
Autors principals: Qureshi, Ammar T., Dey, Devaveena, Sanders, Erin M., Seavey, Jonathan G., Tomasino, Allison M., Moss, Kaitlyn, Wheatley, Benjamin, Cholok, David, Loder, Shawn, Li, John, Levi, Benjamin, Davis, Thomas A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809339/
https://ncbi.nlm.nih.gov/pubmed/29029772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.07.010
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