In Vivo Brain Glycine and Glutamate Concentrations in Patients with First-Episode Psychosis Measured by Echo-Time-Averaged Proton MR Spectroscopy at 4 Tesla

BACKGROUND: Accumulating evidence suggests the involvement of abnormal glutamateric neurotransmission and N-methyl-D-aspartate receptor (NMDAR) hypofunction in the pathophysiology of psychotic disorders. The purpose of this study was to quantify in vivo glutamate (Glu) and glycine (Gly) levels in pa...

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Udgivet i:Biol Psychiatry
Main Authors: Kim, Sang-Young, Kaufman, Marc J., Cohen, Bruce M., Jensen, J. Eric, Coyle, Joseph T., Du, Fei, Öngür, Dost
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809251/
https://ncbi.nlm.nih.gov/pubmed/29031411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.08.022
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