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One Step Fabrication of Hydrogel Microcapsules with Hollow Core for Assembly and Cultivation of Hepatocyte Spheroids

3D hepatic microtissues can serve as valuable liver analogues for cell-based therapies and for hepatotoxicity screening during preclinical drug development. However, hepatocytes rapidly dedifferentiate in vitro, and typically require 3D cultures systems or co-cultures for phenotype rescue. In this w...

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Vydáno v:Acta Biomater
Hlavní autoři: Siltanen, Christian, Diakataou, Michaela, Lowen, Jeremy, Haque, Amranul, Rahimian, Ali, Stybayeva, Gulnaz, Revzin, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809154/
https://ncbi.nlm.nih.gov/pubmed/28069506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.01.010
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