Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study

BACKGROUND: Squamous cell carcinoma of the anal canal (SCCA) is a rare malignancy associated with infection by human papillomavirus (HPV). No consensus treatment approach exists for the treatment of metastatic disease. Because intratumoral HPV oncoproteins upregulate immune checkpoint proteins such...

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Detalhes bibliográficos
Publicado no:Lancet Oncol
Main Authors: Morris, Van K, Salem, Mohamed E, Nimeiri, Halla, Iqbal, Syma, Singh, Preet, Ciombor, Kristen, Polite, Blase, Deming, Dustin, Chan, Emily, Wade, James L, Xiao, Lianchun, Bekaii-Saab, Prof Tanios, Vence, Luis, Blando, Jorge, Mahvash, Armeen, Foo, Wai Chin, Ohaji, Chimela, Pasia, Manolo, Bland, Gail, Ohinata, Aki, Rogers, Jane, Mehdizadeh, Amir, Banks, Kimberly, Lanman, Richard, Wolff, Robert A, Streicher, Howard, Allison, Prof James, Sharma, Prof Padmanee, Eng, Prof Cathy
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809128/
https://ncbi.nlm.nih.gov/pubmed/28223062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30104-3
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