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Methods for the development of in silico GPCR models
The Reggio group has constructed computer models of the inactive and G-protein activated states of the cannabinoid CB1 and CB2 receptors, as well, several orphan receptors that recognize a sub-set of cannabinoid compounds, including GPR55 and GPR18. These models have been used to design ligands, mut...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5809125/ https://ncbi.nlm.nih.gov/pubmed/28750813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.05.005 |
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