A Facile Method for Somatic, Lifelong Manipulation of Multiple Genes in the Mouse Liver

Current techniques for the alteration of gene expression in the liver have a number of limitations, including the lack of stable somatic gene transfer and the technical challenges of germline transgenesis. Rapid and stable genetic engineering of the liver would allow systematic, in vivo testing of c...

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Publicado en:Hepatology
Main Authors: Wangensteen, Kirk J., Wilber, Andrew, Keng, Vincent W., He, Zhiying, Matise, Ilze, Wangensteen, Laura, Carson, Corey M., Chen, Yixin, Steer, Clifford J., McIvor, R. Scott, Largaespada, David A., Wang, Xin, Ekker, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808937/
https://ncbi.nlm.nih.gov/pubmed/18435462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22195
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