Hypoxia: Signaling in the Metastatic Cascade

Hypoxia is a potent microenvironmental factor that promotes tumor metastasis. Recent studies have revealed mechanisms by which hypoxia and activation of hypoxia inducible factor (HIF) dependent signaling promotes metastasis through the regulation of metabolic reprogramming, the stem cell phenotype,...

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: Rankin, Erinn B., Nam, Jin-Min, Giaccia, Amato J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808868/
https://ncbi.nlm.nih.gov/pubmed/28741527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.05.006
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https://ncbi.nlm.nih.gov/pmc/articles/PMC5808868/
https://ncbi.nlm.nih.gov/pubmed/28741527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.05.006